CryoBio
- Pre-Seed
- Agriculture



Murli Manohar
CEO & Co-Founder

Abe Pressman
Lead Frost Scientist & Co-Founder
Team brings extensive experience in biotech R&D and in translating discoveries into market-ready products.
Contact UsWe are developing a novel, nature-inspired solution to fight agricultural frost, protecting 5% of production while slashing emissions.
Frost is a growing agricultural problem, worsened by climate change. It is estimated to damage 5% of total crops worth over $50B, enough to feed an additional 200M people. Despite increased frost severity and frequency, current equipment-based methods are prohibitively expensive and barely effective. CryoBio technology works uniquely by lowering water's freezing temperature by up to 8°C, providing unmatched frost protection at a cost less than 1/10th of current methods. At its full potential, it can offer near-total protection against the most severe frost.
>$50 billion
annual crop value shielded by frost defense technologies
CryoBio is in pursuit of transforming how we protect crops from frost, a worsening agricultural disaster, while contributing to sustainably feeding the planet.
Problem
As climate change continues to escalate, the damaging effects of frost on agriculture are becoming increasingly severe. By the next decade, it is estimated to destroy 5% of global agricultural yields, worth over $50 billion, and enough food to feed over 200 million people. At the individual farm level, produce losses can reach 90%, severely affecting farmers' livelihoods. Despite the urgency of the situation, current methods of combating frost are ineffective and prohibitively expensive, leaving the majority of farmers feeling helpless.
In 2023, we lost nearly 70% of our produce, and we are still recovering from that loss. If the efficacy of technology proven in farm, we’d use it on every acre.
Vineyard Farm Manager
Watkins Glen, NY


Solution
CryoBio’s innovation addresses the heart of the problem by offering an effective and affordable solution. Our breakthrough technology leverages natural molecules derived from cold-adapted organisms. It can be applied to any crop with standard equipment before anticipated frost at less than one-tenth the cost of existing methods, and it uniquely works by preventing ice formation on plants. The technology is so powerful that it can protect crops from the most severe frost known to date without harming the environment while improving farmers' livelihoods and agricultural resilience.
Media About Us —


LinkedIn Post
October 30, 2025CryoBio Wins 3rd Place at the FuzeHub Commercialization Competition!


LinkedIn post
June 09, 2025Rev: Ithaca Startup Works


LinkedIn post
April 30, 2025From crop failure to crop resilence


Podcast
April 20, 2025Spilled Salt Podcast w/ Murli Manohar


Achievement
May 18, 2025